Heart inflammation following COVID-19 vaccination was higher than expected in multiple age groups and was particularly pronounced in young men, according to a new data analysis from Centers for Disease Control and Prevention (CDC) researchers.

Analyzing records submitted to the Vaccine Adverse Event Reporting System (VAERS) between December 2020 and August 2021, the researchers found that young males aged 12 to 17 were the most likely to suffer post-vaccination myocarditis, a form of heart inflammation that can lead to death.

The rates were the highest after the second dose and after vaccination with the Pfizer-BioNTech jab. Males aged 12 to 15 experienced 70.7 myocarditis cases per million doses administered and males aged 16 or 17 experienced 105.8 cases per million doses, according to the peer-reviewed study, published in the Journal of the American Medical Association.

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